Letrozole: Description of the Drug
Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. As an aromatase inhibitor, it functions by reducing estrogen levels in the body, thereby slowing or stopping the growth of certain types of breast tumors that require estrogen to grow.
Mechanism of Action
The description of the drug reveals that letrozole inhibits the aromatase enzyme, which is responsible for converting androgens into estrogens in peripheral tissues. By blocking this enzyme, letrozole effectively decreases the overall estrogen production, making it less available for cancer cells to utilize.
Clinical Uses
Letrozole is mainly prescribed for:
- Adjuvant treatment of hormone https://letrozolebodybuilding.com/product/femara-2-5mg-eurimpharm/ receptor-positive breast cancer in postmenopausal women.
- First-line treatment for locally advanced or metastatic breast cancer.
- As a fertility treatment in certain cases, where it stimulates ovulation.
Dosage and Administration
The typical dosage of letrozole is 2.5 mg taken orally once daily. Treatment duration varies based on individual patient circumstances, including the stage of cancer and response to therapy. It’s essential for patients to follow their healthcare provider’s instructions regarding dosage and administration.
Side Effects
- Hot flashes
- Joint pain or stiffness
- Fatigue
- Nausea
Serious side effects can occur, including bone fractures, high cholesterol levels, and liver function changes. Regular monitoring by healthcare professionals is crucial during treatment.
Conclusion
In summary, the description of the drug letrozole highlights its critical role in treating hormone-sensitive breast cancer among postmenopausal women. Understanding its mechanism of action, uses, and potential side effects can help patients manage their treatment plan effectively while working closely with their healthcare providers.